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Toast Of New York must break from stall nine in the Breeders' Cup Classic at Santa Anita this weekend.
Jamie Osborne's inmate is the sole European challenger declared for the main event and will again be ridden by Jamie Spencer.
The UAE Derby winner finished second in the Pacific Classic behind Shared Belief, who will bid to uphold the form from gate six.
California Chrome, the Kentucky Derby hero, has a wide draw in trap 13, with Cigar Street and Tonalist in stalls two and 11 respectively.
Magician will defend his Breeders' Cup Turf crown from stall eight.
Aidan O'Brien's four-year-old warmed up for the Grade One with a fine second in the Arlington Million in August.
He will again be ridden by the trainer's son, Joseph O'Brien.
Ballydoyle are also responsible for Chicquita, who blew her chance on Champions Day at Ascot when she hung badly left in the British Champions Fillies & Mares Stakes.
Frankie Dettori has been charged with keeping the daughter of Montjeu on the straight and narrow from stall 11.
Ryan Moore partners Sir Michael Stoute's Telescope, who is drawn in stall one, while Brown Panther (four) and Flintshire (seven) add further strength in depth for the European charge.
Richard Hannon's Toronado goes from trap five in the Breeders' Cup Mile, in which compatriot Trade Storm has been handed berth eight.
Royal Ascot winner Mustajeeb has also been declared.
Dermot Weld's three-year-old colt finished third in the Irish Derby and was a good second behind Bow Creek when last sighted in the Boomerang Mile at Leopardstown.
Pat Smullen is again given the chance to shine aboard the Nayef colt, who goes from stall four.
France is strongly represented by Anodin (nine), Veda (three) and Karakontie (14).
Dank, trained by Stoute and ridden by Moore, won the Filly & Mare Turf 12 months ago and is back for another go in stall three.
She is joined in the line-up by Just the Judge (two) and Secret Gesture (five).
Irish trainer Willie McCreery sets sail in the race with Fiesolana.
The five-year-old mare claimed the scape of Rizeena in the Matron Stakes at Leopardstown on her penultimate outing but she could only finish sixth in the Prix de la Foret at Longchamp.
Flaxman Stables' representative will be partnered by Billy Lee, who must guide Fiesolana from out of gate six.
Smullen also receives the leg-up aboard Caspar Netscher in the Breeders' Cup Turf Sprint, for which the partnership race from stall 13.
David Simcock's five-year-old made a dramatic return to form at Woodbine a few weeks ago when he claimed Grade Two glory in the Nearctic Stakes.
Ballydoyle rely upon The Great War in the Breeders' Cup Juvenile.
A three-and-a-half-length winner of the Blenheim Stakes at the Curragh in September, Moore's companion goes from stall four in the 13-runner field.
O'Brien's strong hand within the two-year-old division if further evidenced by War Envoy's presence in the Breeders' Cup Juvenile Turf on Friday.
He will break from stall seven after having previously finished fifth in the Prix Jean-Luc Lagardere at Longhchamp.
Aktabantay was one place behind War Envoy at Longchamp and is also in the hunt in the hands of Olivier Peslier.
Hugo Palmer's Solario Stakes winner has been drawn in trap nine.
The Charlie Fellowes-trained Wet Sail is in stall one, with Charlie Hills' Commemorative in four.
Dettori rides Royal Ascot winner Hootenanny (five).
O'Brien also goes to war with Qualify in the Juvenile Fillies Turf.
The young daughter of Fastnet Rock was a decisive winner of a Group Three at the Curragh in September and will be ridden for the first time by Moore.
Qualify has been given a wide draw in stall 14, with the Osborne-trained Prize Exhibit one away in gate 13.
Osaila (two) is also engaged for Hannon and owners Al Shaqab Racing.
French contender L'Amour De Ma Vie (one) is the only European raider in the Breeders' Cup Distaff.