Holy Bull (January 24, 1991 – June 7, 2017) was a champion Thoroughbred racehorse. Although he finished a disappointing twelfth in the 1994 Kentucky Derby, his major wins that year in the Florida Derby, Blue Grass Stakes, Metropolitan Handicap, Haskell Invitational, Travers Stakes and Woodward Stakes earned him American Horse of the Year honors. He suffered a career-ending injury in the Donn Handicap soon after the beginning of his four-year-old campaign in 1995.

Subsequently, retired to stud, he was the sire of Kentucky Derby winner Giacomo and champion two-year-old Macho Uno.

Holy Bull was ranked #64 on the Blood-Horse magazine's list of the Top 100 U.S. racehorses of the 20th Century and was inducted into the National Museum of Racing and Hall of Fame in 2001.